Historical Marker

Headache Springs, C.S.A. Medical Laboratory

Tyler · Smith County · Dedicated 1965 · THC Atlas #5423007732

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Marker Inscription

A quarter mile north of this site is "Headache Springs," noted for its healing mineral waters. During the Civil War, as sea blockades cut off imports, a Confederate medical laboratory operated here. One of nine, and only one west of Mississippi River. For the government it made medicines and whiskey. The army at this time was buying medicinal herbs, including poke root, snakeroot, mullein, jimson weed, Jerusalem oak, nightshade, mistletoe and cherry bark. With mineral salts, these were the medicines of desperation.

About this site

Headache Springs, C.S.A. Medical Laboratory is a historical marker in Tyler, Smith County, dedicated in 1965. It is one of 90 historical markers documented in Smith County in the Texas Historical Commission Atlas, among 272 historic sites cataloged across the county.

The site sits at 32.3330, -95.2479 near Tyler. The nearest cataloged historic site is Universe Cemetery (cemetery), about 0.2 miles away. Others within a short drive include Belcher Cemetery, Liberty Hill Memorial, and Liberty Hill.

This record corresponds to Texas Historical Commission Atlas #5423007732. Use the map below for its exact position and turn-by-turn directions.

📍 32.3330, -95.2479 · Tyler, Smith County
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